Reticular erythematous mucinosis pathology dermnet nz. Reticular erythematous mucinosis rem syndrome in twins. However, ofm does not show invasion into adjacent tissues and also lacks reticular fibres 4. It presents with reticular, macular lesions or erythematous papules and plaques. Mucinosis eritematosa reticular actas dermosifiliogr 2004. Reticular erythematous mucinosis rem is a rare, benign skin condition that causes welldefined red rashes on the skin. Reticular erythematous mucinosis scleredema scleromyxedema papular mucinosis acral persistent papular mucinosis focal mucinosis digital mucous cyst mucocele cutaneous myxoma cutaneous mucinosis of infancy nevus mucinosis alopecia mucinosa follicular mucinosis mucopolysaccharidoses thursday, may 23.
Reticular erythematous mucinosis rem is characterized by persistent, mildly pruritic, reticulated erythematous macules, papules or urticarial plaques that most often occur on the upper back and chest figure 1. Aug 01, 2012 reticular erythematous mucinosis rem is a rare cutaneous condition often referred to as plaque. Reticular erythematous mucinosis mdedge dermatology. This is a 28 year old woman who presents with a reticulated rash on her chest. At present, almost 100 patients with rem syndrome have been described. It is a disease that tends to affect women in the third and fourth decades of life 187 see also. The injuries of follicular mucinosis usually are located in head or more rarely to become general to neck, trunk and extremities.
The possible complications from reticular erythematous mucinosis include. Assoc prof patrick emanuel, dermatopathologist, auckland, new zealand, 2014. The area is photosensitive and has been present for 1 year without resolution and without new lesions. However, both cases had features that differed from previous descriptions. Reticular erythematous mucinosis syndrome rem syndrome. Reticular erythematous mucinosis rem, rem syndrome.
Reticular erythematous mucinosis icd10cm alphabetical index. Mucinosis eritematosa reticular reticular erythematous. Reticular erythematous mucinosis, journal of the european. Initially reported as a plaquelike form of cutaneous mucinosis pcm and rem syndrome, 1 these conditions were recognized as part of the spectrum of the same disorder. Reticular erythematous mucinosis rem, rem syndrome, plaque. Two female patients had eruptions with the morphologic and histologic features of reticular erythematous mucinosis syndrome. Jan 06, 2010 reticular erythematous mucinosis rem is a rare chronic dermatosis with a predilection for anterior and posterior trunk typically. Learn more about reticular erythematous mucinosis from related diseases, pathways, genes and ptms with the novus bioinformatics tool. Reticular erythematous mucinosis rem is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides. Pdf on dec 1, 2018, daniel morgadocarrasco and others published. Hiromasa nikai, in diagnostic surgical pathology of the head and neck second edition, 2009. Centers of lesions may be slightly hyperpigmented and depressed relative to their borders generalized few to thousands of 12 mm, fleshcolored to.
Mucinosis eritematosa reticular actas dermosifiliograficas. Llinear morphea with secondary mucinosisinear morphea with. In one case the eruption developed three to four weeks after a single erythemogenic sun exposure and. Reticular erythematous mucinosis is a rare chronic diffuse form of primary idiopathic mucinosis. Cutaneous lesions range from erythematous papules and plaques to reticular macular erythema. On alcian blue periodic acid schiff stain, abundant mucin deposition was demonstrated in the upper reticular dermis figure 3b. Reticular erythematous mucinosis is a rare syndrome which can be misdiagnosed as seborrhoeic dermatitis. On clinical examination, it presents as a painless mass and has the same color as the surrounding mucosa. Induction of the disease has been associated with viral processes, solar irradiation, specific. Dermis mucinose eritematosa reticulada information on. Dermatomyosites presenting as plaquelike mucinosis. The patient was treated with hydroxychloroquine 400 mg.
This case demonstrates a possible relationship between reticular erythematous. Oral focal mucinosis is the microscopic counterpart of the cutaneous focal mucinosis or cutaneous myxoid cyst. Treatment of reticular erythematous mucinosis with uva1. Gaclinical presentations localized groups of 12 mm fleshcolored to erythematous papules, often in an annular arrangement, over distal extremities. Reticular erythematous mucinosis definition of reticular. Papules small bumps develop on the midback or chest and form a netlike pattern hence the name, reticular.
These are most commonly seen on the chest and upper back. A repeat skin biopsy performed at our institute showed epidermal atrophy, hyalinization of collagen throughout the dermis and mucin deposition in upper reticular dermis figure 3a. Jan 11, 2019 reticular erythematous mucinosis rem is a rare, benign skin condition that causes welldefined red rashes on the skin. Examination of biopsy specimen showed focal mucin deposition in papillary and upper reticular dermis. Since it was not possible to relate these findings to any known syndrome, a combination of the main signs, reticular erythema and mucinosis, was used to name this entity rem syndrome. Altman division of comparative pathology, department of pathology, school of medicine, university of miami, miami, fl abstract.
Midline mucinosis has been previously reported in prepubertal children but is rare. Reticular erythematous mucinosis or rem is a rare dermatosis characterised by papules and plaques on the upper trunk which often coalesce into a reticulated pattern. Dermis sindrome rem o mucinosis reticular eritematosa. Reticular erythematous mucinosis and lupus erythematosus. Reticular erythematous mucinosis what exactly is this.
Although the exact etiology remains undefined, efforts to elucidate pathogenesis, disease associations, and prospective. Complete resolution of indurated erythematous plaque on the upper back and nap of the neck except post inflammatory hyperpigmentation. Rem requires both a clinical and a pathological diagnosis. Rem increases the risk of thyroid disease, such as hashimotos thyroiditis, diabetes mellitus, and arthritis.
Pretibial mucinosis in a patient without graves disease. Reticular erythematous mucinosis rem is a rare cutaneous condition often referred to as plaquelike mucinosis and midline mucinosis. Although the exact etiology remains undefined, efforts to elucidate pathogenesis, disease associations, and prospective treatment modalities have been encouraging. Reticular erythematous mucinosis rem is a rare entity characterized by infiltrated erythematous plaques on exposed areas of the thorax and back. Follicular mucinosis is a disorder histopathologically defined by the accumulation of mucin in hair follicles and sebaceous glands, which undergo epithelial reticular degeneration. There are 0 terms under the parent term reticular erythematous mucinosis in the icd10cm alphabetical index. What is reticular erythematous mucinosis reticular erythematous mucinosis rem is rare form of cutaneous mucinosis. The central chest andor upper back area is a preferentially involved location. It has been related to sun exposure, hormonal alterations, rheumatological processes and breast cancer. She has been on topical and oral steroids without resolution. Cutaneous mucinosis in dermatomyositis associated with a malignant tumor. We report the case of a 51yearold man who presented with reticular macular erythema and erythematous plaques on the midline of the back of 10 years duration that seemed to worsen on exposure to sunlight. Cutaneous mucinosis is part of a heterogeneous group of disorders characterized by localized or diffuse dermal mucin deposit.
What are the possible complications of reticular erythematous mucinosis. Cutaneous lupus mucinosis also known as papular and nodular mucinosis in lupus erythematosus, papular and nodular mucinosis of gold, and papulonodular mucinosis in lupus erythematosus is a cutaneous condition characterized by lesions that present as asymptomatic skincolored, at times reddish, 0. Reticular erythematous mucinosis on the midline of the. Discussion lm is an idiopathic cutaneous mucinosis which was first described by montgomery and underwood in 1953. It is also called midline mucinosis or plaquelike cutaneous mucinosis.
Case report open access diagnosis and treatment of oral focal mucinosis. It is believed that follicular keratinocytes are responsible for mucin production, as a response to the stimulus of cytokines released by perifollicular t lymphocytes. The reticular pattern with involvement of the midline of the chest and back, the predilection for middleaged women, the controversial relationship with photosensitivity and the. Suarezamor and others published mucinosis eritematosa reticular. Although the exact etiology remains undefined, efforts to. Reticular erythematous mucinosis rem is rare form of cutaneous mucinosis. Background reticular erythematous mucinosis rem is an uncommon disease, the nosology and specific characteristics of which are controversial because most reports deal with single cases or small series. Mucinosis eritematosa reticular reticular erythematous mucinosis. Mucocele is a common lesion of the oral cavity showing myxoid areas with granulation tissue which is not seen in oral focal mucinosis. Reticular erythematous mucinosis the icd10cm alphabetical index is designed to allow medical coders to look up various medical terms and connect them with the appropriate icd codes. Adult variant of selfhealing cutaneous mucinosis in a.
Icd10cm alphabetical index reticular erythematous mucinosis. Cutaneous mucinosis covers a heterogeneous group of diseases involving a diffuse and or focal mucin accumulation in the skin and its annexes. Distinguishing features included normalappearing collagen in the papillary dermis 1212 with graves disease and 06 without, mucin deposition in the reticular dermis 1212 with graves. Reticular erythematous mucinosis rem syndrome is a rare, chronic disease characterized by asymptomatic, persistent reticular, slightly infiltrated erythematous plaques on chest andor back with slight infiltration. Mucinous disorders of the skinbeyond the dermal mucinosis. Dermis mucinose eritematosa reticulada information on the. Reticular erythematous mucinosis rem, first described relatively recently, is characterized by reticulated erythematous papules coalescing into a plaque on the midupper back or midchest. Seven dogs had one or more asymptomatic nodules, papules, or plaques on the skin or oral.
Ideal sources for wikipedia s health content are defined in the guideline wikipedia. It is a disease that tends to affect women in the third and fourth decades of life. Mucinosis papulosa acral persistente 39 med cutan iber lat am 20056. While the etiology of ofm remains unknown, a possible cause is.
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